Impact of Adenoviral Transduction With SREBP1c or AMPK on Pancreatic Islet Gene Expression Profile: Analysis With Oligonucleotide Microarrays
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چکیده
منابع مشابه
Impact of adenoviral transduction with SREBP1c or AMPK on pancreatic islet gene expression profile: analysis with oligonucleotide microarrays.
Accumulation of triglyceride in islets may contribute to the loss of glucose-stimulated insulin secretion (GSIS) in some forms of type 2 diabetes (Diraison et al., Biochem J 373:769-778, 2004). Here, we use adenoviral vectors and oligonucleotide microarrays to determine the effects of the forced expression of SREBP1c on the gene expression profile of rat islets. Sterol regulatory element bindin...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2004
ISSN: 0012-1797,1939-327X
DOI: 10.2337/diabetes.53.suppl_3.s84